[Biostatistics and Bayes]: Comment
نویسندگان
چکیده
منابع مشابه
Nonparametric Bayes Applications to Biostatistics
1. Introduction Biomedical research has clearly evolved at a dramatic rate in the past decade, with improvements in technology leading to a fundamental shift in the way in which data are collected and analyzed. Before this paradigm shift, studies were most commonly designed to be simple and to focus on relationships among a few variables of primary interest. For example, in a clinical trial, pa...
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Through his various examples, Professor Efron makes a convincing case that cutting-edge science requires methods for detecting multiple “non-nulls.” These methods must be straightforward to implement, but perhaps more importantly statisticians need to be able to justify them unambiguously. Efron’s Empirical Bayes approach is certainly computationally efficient, but we feel the rationale for mak...
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Brad Efron’s paper has inspired a return to the ideas behind Bayes, frequency and empirical Bayes. The latter preferably would not be limited to exchangeable models for the data and hyperparameters. Parallels are revealed between microarray analyses and profiling of hospitals, with advances suggesting more decision modeling for gene identification also. Then good multilevel and empirical Bayes ...
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ژورنال
عنوان ژورنال: Statistical Science
سال: 1990
ISSN: 0883-4237
DOI: 10.1214/ss/1177012097